We use cookies to offer you the best experience on our site. You can find out more about the cookies we use or disable them in the Cookie settings
Labeling Reagents
Biotins & streptavidin derivatives
Streptavidin-biotin interaction
The streptavidin-biotin interaction, at a dissociation constant of (Kd) on the order of ~10-14 mol/L, is one of the strongest non-covalent interactions known in nature, typically occurring between a protein and a ligand.
The complex is resistant to pH, organic solvents and other denaturing agents making this interaction very stable and hence attributes to its importance in a number of biological applications including Western blotting, IHC, ELISA and FACS.