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Beta-Amyloid (1-40) Peptide
- Cat.Number : AS-24235-
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Aß (1-40) together with Aß (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs. These undergo post-secretory aggregation and deposition in the Alzheimer’s disease brain.
Electron microscopy of b-amyloid (1-40) stained with Thioflavin T (data generated by an AnaSpec scientist).
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Citations
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Identifying the minimal Cu and Zn binding site sequence in amyloid beta peptides.
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Microchip electrophoresis profiling of Aβ peptides in the cerebrospinal fluid of patients with Alzheimer’s disease.
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Beta-amyloid peptide blocks the fast-inactivating K+ current in rat hippocampal neurons.
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Cholesterol depletion inhibits the degradation of amyloid β-peptide in rat pheochromocytoma (PC12) cells.
Neurosci. Lett. . 2005 Sep 09 ; 391(1-2) 71 | DOI : 10.1016/j.neulet.2005.08.034.
- ZX. Sun
- et al
A novel compound RS-0466 reverses β-amyloid-induced cytotoxicity through the Akt signaling pathway in vitro.
Eur J Pharmacol . 2002 Dec 13 ; 457(1) 11 | DOI : 10.1016/s0014-2999(02)02657-2
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N-truncation and pyroglutaminylation enhances the opsonizing capacity of Aβ-peptides and facilitates phagocytosis by macrophages and microglia.
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