Peptides

[Lys(Ac)16]-Histone H4 (1-21)-GGK(Biotin) - 1 mg

326.00
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  • Cat.Number : AS-64847-1
  • Availability :
    In production

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This peptide is histone H4 amino acids 1 to 16, acetylated at Lys-16 and at the N-terminus. This peptide also contains a GG linker, followed by a biotinylated lysine. The acetylation of histone H4 causes structural changes that play a crucial role in amplifying the binding of transcription factors to specific recognition sites within the nucleosome.

Specifications

Chemistry
Sequence one letter code
  • Ac-SGRGKGGKGLGKGGA-K(Ac)-RHRKV-GGK(Biotin)
Sequence three letter code
  • Ac-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2644.2
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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Citations

Selective recognition of H3.1K36 dimethylation/H4K16 acetylation facilitates the regulation of all-trans-retinoic acid (ATRA)-responsive genes by putative chromatin reader ZMYND8

J. Biol. Chem. . 2015 Dec 11 ; 291(6) 2664 | DOI : 10.1074/jbc.M115.679985

  • S. Adhikary
  • et al

Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.

PNAS . 2014 Mar 10 ; 111(12) E1072 | DOI : 10.1073/pnas.1319122111

  • C. Das
  • et al