Tube of Human MOG (1-125), Recombinant protein
Protein

Recombinant human MOG (1-125)

€254.00
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  • Cat.Number : AS-55158-100
  • Availability :
    In stock
  • Shipping conditions : Ice delivery fees must be applied

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Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys

The sequence (Accession # CAQ10087) corresponding to the extracellular domain of human MOG along with a 6x His tag was expressed in E. coli. The recombinant human MOG (H-rMOG) was purified from urea denatured bacterial lysate using immobilized metal affinity chromatography (IMAC). The molecular mass of the recombinant human MOG is 14.2 kDa

Specifications

Chemistry
UniProt number
  • Q16653
Molecular Mass/ Weight
  • 14.2 kDa
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Concentration
  • 1 mg/ml
Purification Method
  • Purified
Purity
  • >95%
Storage & stability
Form
  • In solution
Resuspension condition
  • human MOG must be thoroughly mixed directly with Complete Freund’s Adjuvant (CFA). Do not dilute recombinant human MOG with buffers that have pH greater than 4.5. Protein will precipitate at pH higher than 4.5
Storage Buffer
  • 25 mM sodium acetate buffer (pH=4.0)
Storage Conditions
  • - 80° C
Activity
Application
Biomarker Target
Specificity
  • human MOG
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Host
Source / Species
  • human
Codes
Code Nacres
  • NA.27

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