Peptides

Secretoneurin - 1 mg

348.00
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  • Cat.Number : AS-62673
  • Availability :
    In production

Quantity

This peptide is amino acids 154 to 186 fragment of secretogranin II, designated secretoneurin. Secretoneurin is a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II. Secretoneurin acts as direct angiogenic cytokine, inhibits endothelial cell (EC) apoptosis, stimulates EC proliferation, and activates the mitogen-activated protein kinase (MAPK) system and the Akt pathway.

Specifications

Chemistry
Sequence one letter code
  • TNEIVEEQYTPQSLATLESVFQELGKLTGPSNQ
Sequence three letter code
  • H-Thr-Asn-Glu-Ile-Val-Glu-Glu-Gln-Tyr-Thr-Pro-Gln-Ser-Leu-Ala-Thr-Leu-Glu-Ser-Val-Phe-Gln-Glu-Leu-Gly-Lys-Leu-Thr-Gly-Pro-Ser-Asn-Gln-OH
CAS registry number
  • 149146-12-3
Molecular Formula
  • C159H252N40O58
Molecular Mass/ Weight
  • 3652.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • mouse, rat
Codes
Code Nacres
  • NA.26

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Citations

GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin

Proc Natl Acad Sci U S A. . 2013 May 20 ; 110(23) 9529 | DOI : 10.1073/pnas.1219004110

  • RC. Meyer
  • et al