Tube of Tat-GluR23Y peptide
Peptides

Tat-GluR23Y - 1 mg

€140.00
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  • Cat.Number : AS-64429
  • Availability :
    In stock

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The synthetic peptide (Tat-Glur23Y) contains tyrosine residues that blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Previous research shows that Tat-Glur23Y blocks regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.

Specifications

Chemistry
Sequence one letter code
  • YGRKKRRQRRRYKEGYNVYG
Sequence three letter code
  • H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gly-OH
Molecular Formula
  • C115H185N43O29
Molecular Mass/ Weight
  • 2634
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HIV
Codes
Code Nacres
  • NA.26

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Citations

Inhibiting PKMζ reveals dorsal lateral and dorsal medial striatum store the different memories needed to support adaptive behavior.

Learn. Mem . 2012 Jan 01 ; 19 307 | DOI : 10.1101/lm.025148.111

  • WM. Pauli
  • et al

Inhibition of PKMζ in nucleus accumbens core abolishes long-term drug reward memory

J Neurosci. . 2011 Apr 06 ; 31(14) 5436 | DOI : 10.1523/JNEUROSCI.5884-10.2011

  • Y. Li
  • et al