Peptides

Transdermal Peptide - 1 mg

81.00
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  • Cat.Number : AS-62066
  • Availability :
    In production

Quantity

This short synthetic peptide facilitates efficient transdermal protein drug delivery through intact skin. Co-administration of the peptide and insulin to the abdominal skin of diabetic rats results in elevated systemic levels of insulin and suppresses serum glucose levels. This peptide creates a transient opening in the skin barrier to enable macromolecular drugs to reach systemic circulation.

Specifications

Chemistry
Sequence one letter code
  • ACSSSPSKHCG
Sequence three letter code
  • H-Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly-OH
Molecular Formula
  • C40H64N14O16S2
Molecular Mass/ Weight
  • 1063.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Codes
Code Nacres
  • NA.26

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Citations

Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape

Biochem J.  . 2011 Apr 15 ; 435(2) 475 | DOI : 10.1042/BJ20101021

  • R. Bartz
  • et al