Manufacturing of RNA vaccines & therapeutics

 

As an RNA vaccine and drug CDMO company, we deliver GMP RNA and GMP mRNA in a quality required for RNA based vaccines and treatments

 

Long RNA

To circumvent chemical synthesis limitation

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mRNA

 With polyA tail and cap   


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Guide RNA

 Used for gene editing technique like CRISPR/Cas9, TALEN or ZFNs

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bp


Sequence lengths from
700 to 6000 nucleotides already tested

g


0.3 to 50 g GMP manufacturing scale

years


CDMO for the manufacturing of GMP Biopharmaceuticals

RNA Services

Our RNA services cover the process development, GMP plasmid production, plasmid linearization
and GMP manufacturing of IVT-RNA API
for use in Tox studies and Human clinical trials.

Starting material

Our flexible service allows various grades and types of customer or Eurogentec sourced templates to be used (circular plasmid, linearized plasmid, or PCR fragments). We also offer plasmid linearization service.

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Modifications

Various co- or post-transcriptional modifications (including capping, poly-adenylation and modified ribonucleotides)

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Manufacturing

Our service offering includes customer process optimization, scale up by Eurogentec and GMP production from 0.3g up to 50 g scale purified RNA for human clinical trials and commercial supply

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Quality control

IVT-RNA are manufactured in GMP accredited facilities. Raw materials and environment are quality tested by qualified staffs. A full QC release on Drug Substance is performed for each RNA production.

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Note: The non-infringement of any patents covering the operation of any process or the use of the product alone or in combination with other for use or sale of the products mentioned above is not warranted by Eurogentec. The customer has the sole responsibility of all and any use of Eurogentec’s products.