Tube of Amylin (1-37) peptide, human peptide, amide
Peptides

Amylin (1-37), Islet Amyloid Polypeptide, IAPP, human, amide - 1 mg

€298.00
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  • Cat.Number : AS-60254-1
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    In stock

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Amylin (1-37) also known as Islet Amyloid Polypeptide, IAPP, is a 37-amino acid hormone co-secreted with insulin by beta cells of the pancreas. It contributes to glycemic control. It is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus.

Specifications

Chemistry
Sequence one letter code
  • KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2 (Disulfide bridge: 2-7)
Sequence three letter code
  • H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge: 2-7)
CAS registry number
  • 122384-88-7
Molecular Formula
  • C165H261N51O55S2
Molecular Mass/ Weight
  • 3903.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human
Codes
Code Nacres
  • NA.26

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Citations

Amylin Enhances Amyloid-β Peptide Brain to Blood Efflux Across the Blood-Brain Barrier.

J Alzheimers Dis. . 2017 Feb 03 ; 56(3) 1087 | DOI : 10.3233/JAD-160800

  • AM. Loqman
  • et al

Heterogeneous amylin fibril growth mechanisms imaged by total internal reflection fluorescence microscopy.

Biochemistry. . 2011 Mar 21 ; 50(14) 2808 | DOI : 10.1021/bi101908m

  • SM. Patil
  • et al

Influence of the Human and Rat Islet Amyloid Polypeptides on Structure of Phospholipid Bilayers: Neutron Reflectometry and Fluorescence Microscopy Studies.

Langmuir . 2016 Apr 21 ; 32(17) 4382 | DOI : 10.1021/acs.langmuir.6b00825

  • A. Junghans
  • et al