Tube of Elafin peptide
Peptides

Elafin - 0.1 mg

$375.00
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  • Cat.Number : AS-61641
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This is a fragment of the elafin (elastase-specific inhibitor), an antiproteinase and antimicrobial (gram-positive and gram-negative respiratory pathogens) molecule that is expressed at epithelial sites. Elafin is a potent inhibitor of HNE and proteinase 3 produced in the skin, and in the airways , which is up-regulated in response to early inflammatory cytokines such as TNF and IL-1. Elafin, along with SLPI, also shares characteristics with antimicrobial defensin-like molecules in being a low molecular weight cationic peptide with the ability to eliminate pulmonary pathogens.

Specifications

Chemistry
Sequence one letter code
  • Cys38-Cys53)
Sequence three letter code
  • Cys38-Cys53)
Molecular Mass/ Weight
  • 5999.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, chimpanzee
Codes
Code Nacres
  • NA.26
Alphabet Assignement

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Citations

Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function.

Arterioscler Thromb Vasc Biol . 2012 Nov 29 ; 33(2) 275 | DOI : 10.1161/​ATVBAHA.112.300474

  • CJ. Kuckleburg
  • PJ. Newman