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Catalog Oligonucleotides
PNA FISH Probes
PNA vs DNA backbone
The backbone of PNAs (Peptide Nucleic Acid) is made of repeating N-(2-aminoethyl)-glycine units linked by peptide bonds. Despite this radical structural change, PNAs are capable of sequence-specific binding in a helix form to its complementary DNA or RNA sequence. Due to its superior binding affinity and chemical/biological stability, PNA has been widely applied in the field of biology.
PNA FISH Probe Details
| Fish Probes | Quantity | Sequence | Specificity |
|---|---|---|---|
| C-rich Telomere Probes | 5 nmol | repeats of CCCTAA | For both human and mouse |
| G-rich Telomere Probes | 5 nmol | repeats of TTAGGG | For both human and mouse |
| Centromere Probes | 5 nmol | AAACTAGACAGAAGCATT | For both human and mouse |
| Centromere Protein B Probes | 5 nmol | ATTCGTTGGAAACGGGA | Human specific |